Reducing Uncertainty: Predictors of Stopping Chemotherapy Early and Shortened Survival Time in Platinum Resistant/Refractory Ovarian Cancer-The GCIG Symptom Benefit Study.
Identifieur interne : 000469 ( Main/Exploration ); précédent : 000468; suivant : 000470Reducing Uncertainty: Predictors of Stopping Chemotherapy Early and Shortened Survival Time in Platinum Resistant/Refractory Ovarian Cancer-The GCIG Symptom Benefit Study.
Auteurs : Felicia T. Roncolato [Australie] ; Florence Joly [France] ; Rachel O'Connell [Australie] ; Anne Lanceley [Royaume-Uni] ; Felix Hilpert [Allemagne] ; Luke Buizen [Australie] ; Aikou Okamoto [Japon] ; Eriko Aotani [Japon] ; Sandro Pignata [Italie] ; Paul Donnellan [Irlande (pays)] ; Amit Oza [Canada] ; Elisabeth Avall-Lundqvist [Suède] ; Jonathan S. Berek [États-Unis] ; Florian Heitz [Allemagne] ; Amanda Feeney [Royaume-Uni] ; Dominique Berton-Rigaud [France] ; Martin R. Stockler [Australie] ; Madeleine King [Australie] ; Michael Friedlander [Australie]Source :
- The oncologist [ 1549-490X ] ; 2017.
Abstract
Clinicians and patients often overestimate the benefits of chemotherapy, and overall survival (OS), in platinum resistant/refractory ovarian cancer (PRROC). This study sought to determine aspects of health-related quality of life and clinicopathological characteristics before starting chemotherapy that were associated with stopping chemotherapy early, shortened survival, and death within 30 days of chemotherapy.
DOI: 10.1634/theoncologist.2017-0047
PubMed: 28596446
Affiliations:
- Allemagne, Australie, Canada, France, Irlande (pays), Italie, Japon, Royaume-Uni, Suède, États-Unis
- Angleterre, Basse-Normandie, Californie, Nouvelle-Galles du Sud, Ontario, Région Normandie, Région de Kantō, Schleswig-Holstein
- Caen, Kiel, Sydney, Tokyo, Toronto
- Université de Sydney, Université de Toronto
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Roncolato</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia felicia.roncolato@ctc.usyd.edu.au.</nlm:affiliation><country wicri:rule="url">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Joly, Florence" sort="Joly, Florence" uniqKey="Joly F" first="Florence" last="Joly">Florence Joly</name><affiliation wicri:level="3"><nlm:affiliation>Centre Francois Baclesse, Caen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Francois Baclesse, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="O Connell, Rachel" sort="O Connell, Rachel" uniqKey="O Connell R" first="Rachel" last="O'Connell">Rachel O'Connell</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Lanceley, Anne" sort="Lanceley, Anne" uniqKey="Lanceley A" first="Anne" last="Lanceley">Anne Lanceley</name><affiliation wicri:level="2"><nlm:affiliation>University College London, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>University College London, London</wicri:cityArea></affiliation></author><author><name sortKey="Hilpert, Felix" sort="Hilpert, Felix" uniqKey="Hilpert F" first="Felix" last="Hilpert">Felix Hilpert</name><affiliation wicri:level="3"><nlm:affiliation>Klinik fur Gynakologie und Geburtshilfe, UKSH, Kiel, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik fur Gynakologie und Geburtshilfe, UKSH, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Buizen, Luke" sort="Buizen, Luke" uniqKey="Buizen L" first="Luke" last="Buizen">Luke Buizen</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Okamoto, Aikou" sort="Okamoto, Aikou" uniqKey="Okamoto A" first="Aikou" last="Okamoto">Aikou Okamoto</name><affiliation wicri:level="3"><nlm:affiliation>The Jikei University School of Medicine, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>The Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Aotani, Eriko" sort="Aotani, Eriko" uniqKey="Aotani E" first="Eriko" last="Aotani">Eriko Aotani</name><affiliation wicri:level="3"><nlm:affiliation>Kitasato Academic Research Organization, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Kitasato Academic Research Organization, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Pignata, Sandro" sort="Pignata, Sandro" uniqKey="Pignata S" first="Sandro" last="Pignata">Sandro Pignata</name><affiliation wicri:level="1"><nlm:affiliation>Istituto Nazionale per lo Studio e la Cura dei Tumori - Fondazione G. Pascale, IRCCS, Napoli (MITO), Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto Nazionale per lo Studio e la Cura dei Tumori - Fondazione G. Pascale, IRCCS, Napoli (MITO)</wicri:regionArea><wicri:noRegion>Napoli (MITO)</wicri:noRegion></affiliation></author><author><name sortKey="Donnellan, Paul" sort="Donnellan, Paul" uniqKey="Donnellan P" first="Paul" last="Donnellan">Paul Donnellan</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Trials Ireland, Galway University Hospital, Galway, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Cancer Trials Ireland, Galway University Hospital, Galway</wicri:regionArea><wicri:noRegion>Galway</wicri:noRegion></affiliation></author><author><name sortKey="Oza, Amit" sort="Oza, Amit" uniqKey="Oza A" first="Amit" last="Oza">Amit Oza</name><affiliation wicri:level="4"><nlm:affiliation>Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Avall Lundqvist, Elisabeth" sort="Avall Lundqvist, Elisabeth" uniqKey="Avall Lundqvist E" first="Elisabeth" last="Avall-Lundqvist">Elisabeth Avall-Lundqvist</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Linköping University, Linköping, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology, Linköping University, Linköping</wicri:regionArea><wicri:noRegion>Linköping</wicri:noRegion></affiliation></author><author><name sortKey="Berek, Jonathan S" sort="Berek, Jonathan S" uniqKey="Berek J" first="Jonathan S" last="Berek">Jonathan S. Berek</name><affiliation wicri:level="2"><nlm:affiliation>Stanford Comprehensive Cancer Institute, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanford Comprehensive Cancer Institute, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Heitz, Florian" sort="Heitz, Florian" uniqKey="Heitz F" first="Florian" last="Heitz">Florian Heitz</name><affiliation wicri:level="1"><nlm:affiliation>AGO Study group and Department of Gynecology & Gynecologic Oncology, Kliniken Essen Mitte (KEM), Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>AGO Study group and Department of Gynecology & Gynecologic Oncology, Kliniken Essen Mitte (KEM), Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Feeney, Amanda" sort="Feeney, Amanda" uniqKey="Feeney A" first="Amanda" last="Feeney">Amanda Feeney</name><affiliation wicri:level="2"><nlm:affiliation>Cancer Research UK & UCL Cancer Trials Centre, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Cancer Research UK & UCL Cancer Trials Centre, London</wicri:cityArea></affiliation></author><author><name sortKey="Berton Rigaud, Dominique" sort="Berton Rigaud, Dominique" uniqKey="Berton Rigaud D" first="Dominique" last="Berton-Rigaud">Dominique Berton-Rigaud</name><affiliation wicri:level="1"><nlm:affiliation>ICO Centre René Gauducheau, Saint Herblain, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>ICO Centre René Gauducheau, Saint Herblain</wicri:regionArea><wicri:noRegion>Saint Herblain</wicri:noRegion><wicri:noRegion>Saint Herblain</wicri:noRegion></affiliation></author><author><name sortKey="Stockler, Martin R" sort="Stockler, Martin R" uniqKey="Stockler M" first="Martin R" last="Stockler">Martin R. Stockler</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="King, Madeleine" sort="King, Madeleine" uniqKey="King M" first="Madeleine" last="King">Madeleine King</name><affiliation wicri:level="1"><nlm:affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Friedlander, Michael" sort="Friedlander, Michael" uniqKey="Friedlander M" first="Michael" last="Friedlander">Michael Friedlander</name><affiliation wicri:level="1"><nlm:affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28596446</idno><idno type="pmid">28596446</idno><idno type="doi">10.1634/theoncologist.2017-0047</idno><idno type="wicri:Area/PubMed/Corpus">000548</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000548</idno><idno type="wicri:Area/PubMed/Curation">000546</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000546</idno><idno type="wicri:Area/PubMed/Checkpoint">000546</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000546</idno><idno type="wicri:Area/Ncbi/Merge">004950</idno><idno type="wicri:Area/Ncbi/Curation">004950</idno><idno type="wicri:Area/Ncbi/Checkpoint">004950</idno><idno type="wicri:Area/Main/Merge">000464</idno><idno type="wicri:Area/Main/Curation">000469</idno><idno type="wicri:Area/Main/Exploration">000469</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Reducing Uncertainty: Predictors of Stopping Chemotherapy Early and Shortened Survival Time in Platinum Resistant/Refractory Ovarian Cancer-The GCIG Symptom Benefit Study.</title><author><name sortKey="Roncolato, Felicia T" sort="Roncolato, Felicia T" uniqKey="Roncolato F" first="Felicia T" last="Roncolato">Felicia T. Roncolato</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia felicia.roncolato@ctc.usyd.edu.au.</nlm:affiliation><country wicri:rule="url">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Joly, Florence" sort="Joly, Florence" uniqKey="Joly F" first="Florence" last="Joly">Florence Joly</name><affiliation wicri:level="3"><nlm:affiliation>Centre Francois Baclesse, Caen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre Francois Baclesse, Caen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="O Connell, Rachel" sort="O Connell, Rachel" uniqKey="O Connell R" first="Rachel" last="O'Connell">Rachel O'Connell</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Lanceley, Anne" sort="Lanceley, Anne" uniqKey="Lanceley A" first="Anne" last="Lanceley">Anne Lanceley</name><affiliation wicri:level="2"><nlm:affiliation>University College London, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>University College London, London</wicri:cityArea></affiliation></author><author><name sortKey="Hilpert, Felix" sort="Hilpert, Felix" uniqKey="Hilpert F" first="Felix" last="Hilpert">Felix Hilpert</name><affiliation wicri:level="3"><nlm:affiliation>Klinik fur Gynakologie und Geburtshilfe, UKSH, Kiel, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Klinik fur Gynakologie und Geburtshilfe, UKSH, Kiel</wicri:regionArea><placeName><region type="land" nuts="2">Schleswig-Holstein</region><settlement type="city">Kiel</settlement></placeName></affiliation></author><author><name sortKey="Buizen, Luke" sort="Buizen, Luke" uniqKey="Buizen L" first="Luke" last="Buizen">Luke Buizen</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Okamoto, Aikou" sort="Okamoto, Aikou" uniqKey="Okamoto A" first="Aikou" last="Okamoto">Aikou Okamoto</name><affiliation wicri:level="3"><nlm:affiliation>The Jikei University School of Medicine, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>The Jikei University School of Medicine, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Aotani, Eriko" sort="Aotani, Eriko" uniqKey="Aotani E" first="Eriko" last="Aotani">Eriko Aotani</name><affiliation wicri:level="3"><nlm:affiliation>Kitasato Academic Research Organization, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Kitasato Academic Research Organization, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region></placeName></affiliation></author><author><name sortKey="Pignata, Sandro" sort="Pignata, Sandro" uniqKey="Pignata S" first="Sandro" last="Pignata">Sandro Pignata</name><affiliation wicri:level="1"><nlm:affiliation>Istituto Nazionale per lo Studio e la Cura dei Tumori - Fondazione G. Pascale, IRCCS, Napoli (MITO), Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto Nazionale per lo Studio e la Cura dei Tumori - Fondazione G. Pascale, IRCCS, Napoli (MITO)</wicri:regionArea><wicri:noRegion>Napoli (MITO)</wicri:noRegion></affiliation></author><author><name sortKey="Donnellan, Paul" sort="Donnellan, Paul" uniqKey="Donnellan P" first="Paul" last="Donnellan">Paul Donnellan</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Trials Ireland, Galway University Hospital, Galway, Ireland.</nlm:affiliation><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Cancer Trials Ireland, Galway University Hospital, Galway</wicri:regionArea><wicri:noRegion>Galway</wicri:noRegion></affiliation></author><author><name sortKey="Oza, Amit" sort="Oza, Amit" uniqKey="Oza A" first="Amit" last="Oza">Amit Oza</name><affiliation wicri:level="4"><nlm:affiliation>Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Avall Lundqvist, Elisabeth" sort="Avall Lundqvist, Elisabeth" uniqKey="Avall Lundqvist E" first="Elisabeth" last="Avall-Lundqvist">Elisabeth Avall-Lundqvist</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Linköping University, Linköping, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Oncology, Linköping University, Linköping</wicri:regionArea><wicri:noRegion>Linköping</wicri:noRegion></affiliation></author><author><name sortKey="Berek, Jonathan S" sort="Berek, Jonathan S" uniqKey="Berek J" first="Jonathan S" last="Berek">Jonathan S. Berek</name><affiliation wicri:level="2"><nlm:affiliation>Stanford Comprehensive Cancer Institute, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Stanford Comprehensive Cancer Institute, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Heitz, Florian" sort="Heitz, Florian" uniqKey="Heitz F" first="Florian" last="Heitz">Florian Heitz</name><affiliation wicri:level="1"><nlm:affiliation>AGO Study group and Department of Gynecology & Gynecologic Oncology, Kliniken Essen Mitte (KEM), Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>AGO Study group and Department of Gynecology & Gynecologic Oncology, Kliniken Essen Mitte (KEM), Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Feeney, Amanda" sort="Feeney, Amanda" uniqKey="Feeney A" first="Amanda" last="Feeney">Amanda Feeney</name><affiliation wicri:level="2"><nlm:affiliation>Cancer Research UK & UCL Cancer Trials Centre, London, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Cancer Research UK & UCL Cancer Trials Centre, London</wicri:cityArea></affiliation></author><author><name sortKey="Berton Rigaud, Dominique" sort="Berton Rigaud, Dominique" uniqKey="Berton Rigaud D" first="Dominique" last="Berton-Rigaud">Dominique Berton-Rigaud</name><affiliation wicri:level="1"><nlm:affiliation>ICO Centre René Gauducheau, Saint Herblain, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>ICO Centre René Gauducheau, Saint Herblain</wicri:regionArea><wicri:noRegion>Saint Herblain</wicri:noRegion><wicri:noRegion>Saint Herblain</wicri:noRegion></affiliation></author><author><name sortKey="Stockler, Martin R" sort="Stockler, Martin R" uniqKey="Stockler M" first="Martin R" last="Stockler">Martin R. Stockler</name><affiliation wicri:level="4"><nlm:affiliation>NHMRC Clinical Trials Centre, University of Sydney, Sydney, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>NHMRC Clinical Trials Centre, University of Sydney, Sydney</wicri:regionArea><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="King, Madeleine" sort="King, Madeleine" uniqKey="King M" first="Madeleine" last="King">Madeleine King</name><affiliation wicri:level="1"><nlm:affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Friedlander, Michael" sort="Friedlander, Michael" uniqKey="Friedlander M" first="Michael" last="Friedlander">Michael Friedlander</name><affiliation wicri:level="1"><nlm:affiliation>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Australia New Zealand Gynaecological Oncology Group (ANZGOG), New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author></analytic><series><title level="j">The oncologist</title><idno type="eISSN">1549-490X</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Clinicians and patients often overestimate the benefits of chemotherapy, and overall survival (OS), in platinum resistant/refractory ovarian cancer (PRROC). This study sought to determine aspects of health-related quality of life and clinicopathological characteristics before starting chemotherapy that were associated with stopping chemotherapy early, shortened survival, and death within 30 days of chemotherapy.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Canada</li><li>France</li><li>Irlande (pays)</li><li>Italie</li><li>Japon</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Basse-Normandie</li><li>Californie</li><li>Nouvelle-Galles du Sud</li><li>Ontario</li><li>Région Normandie</li><li>Région de Kantō</li><li>Schleswig-Holstein</li></region><settlement><li>Caen</li><li>Kiel</li><li>Sydney</li><li>Tokyo</li><li>Toronto</li></settlement><orgName><li>Université de Sydney</li><li>Université de Toronto</li></orgName></list><tree><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Roncolato, Felicia T" sort="Roncolato, Felicia T" uniqKey="Roncolato F" first="Felicia T" last="Roncolato">Felicia T. Roncolato</name></region><name sortKey="Buizen, Luke" sort="Buizen, Luke" uniqKey="Buizen L" first="Luke" last="Buizen">Luke Buizen</name><name sortKey="Friedlander, Michael" sort="Friedlander, Michael" uniqKey="Friedlander M" first="Michael" last="Friedlander">Michael Friedlander</name><name sortKey="King, Madeleine" sort="King, Madeleine" uniqKey="King M" first="Madeleine" last="King">Madeleine King</name><name sortKey="O Connell, Rachel" sort="O Connell, Rachel" uniqKey="O Connell R" first="Rachel" last="O'Connell">Rachel O'Connell</name><name sortKey="Stockler, Martin R" sort="Stockler, Martin R" uniqKey="Stockler M" first="Martin R" last="Stockler">Martin R. Stockler</name></country><country name="France"><region name="Région Normandie"><name sortKey="Joly, Florence" sort="Joly, Florence" uniqKey="Joly F" first="Florence" last="Joly">Florence Joly</name></region><name sortKey="Berton Rigaud, Dominique" sort="Berton Rigaud, Dominique" uniqKey="Berton Rigaud D" first="Dominique" last="Berton-Rigaud">Dominique Berton-Rigaud</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Lanceley, Anne" sort="Lanceley, Anne" uniqKey="Lanceley A" first="Anne" last="Lanceley">Anne Lanceley</name></region><name sortKey="Feeney, Amanda" sort="Feeney, Amanda" uniqKey="Feeney A" first="Amanda" last="Feeney">Amanda Feeney</name></country><country name="Allemagne"><region name="Schleswig-Holstein"><name sortKey="Hilpert, Felix" sort="Hilpert, Felix" uniqKey="Hilpert F" first="Felix" last="Hilpert">Felix Hilpert</name></region><name sortKey="Heitz, Florian" sort="Heitz, Florian" uniqKey="Heitz F" first="Florian" last="Heitz">Florian Heitz</name></country><country name="Japon"><region name="Région de Kantō"><name sortKey="Okamoto, Aikou" sort="Okamoto, Aikou" uniqKey="Okamoto A" first="Aikou" last="Okamoto">Aikou Okamoto</name></region><name sortKey="Aotani, Eriko" sort="Aotani, Eriko" uniqKey="Aotani E" first="Eriko" last="Aotani">Eriko Aotani</name></country><country name="Italie"><noRegion><name sortKey="Pignata, Sandro" sort="Pignata, Sandro" uniqKey="Pignata S" first="Sandro" last="Pignata">Sandro Pignata</name></noRegion></country><country name="Irlande (pays)"><noRegion><name sortKey="Donnellan, Paul" sort="Donnellan, Paul" uniqKey="Donnellan P" first="Paul" last="Donnellan">Paul Donnellan</name></noRegion></country><country name="Canada"><region name="Ontario"><name sortKey="Oza, Amit" sort="Oza, Amit" uniqKey="Oza A" first="Amit" last="Oza">Amit Oza</name></region></country><country name="Suède"><noRegion><name sortKey="Avall Lundqvist, Elisabeth" sort="Avall Lundqvist, Elisabeth" uniqKey="Avall Lundqvist E" first="Elisabeth" last="Avall-Lundqvist">Elisabeth Avall-Lundqvist</name></noRegion></country><country name="États-Unis"><region name="Californie"><name sortKey="Berek, Jonathan S" sort="Berek, Jonathan S" uniqKey="Berek J" first="Jonathan S" last="Berek">Jonathan S. Berek</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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